About Growth Factors: EGF, KGF and Il-1a
Growth factors are naturally occurring signaling proteins that play a crucial role in cell communication, repair, and rejuvenation. At birth, our skin is rich in these proteins, which help maintain healthy skin functions such as collagen, elastin, and hyaluronic acid production—keeping the skin firm, smooth, and hydrated.
As early as our 20s, the natural production of growth factors begins to decline, slowing cell turnover and repair. This process accelerates with age, particularly during menopause, leading to visible signs of aging such as sagging skin, fine lines, and wrinkles. BIOEFFECT skincare aims to slow down the skin’s aging process by using growth factors as the key ingredient.
The key growth factors in our skin are:
• Epidermal Growth Factor (EGF): Stimulates cell renewal, collagen production, and wound healing.
• Keratinocyte Growth Factor (KGF): Supports skin barrier function and hydration by promoting keratinocyte proliferation.
• Interleukin-1 Alpha (IL-1a): Plays a role in inflammation and skin regeneration, helping to initiate repair processes.
By using a replica of these three human growth factors in the BIOEFFECT skincare line, our products target key visible signs of aging. These growth factors work in synergy to support the skin’s natural production of collagen and elastin, leaving it visibly firmer and rejuvenated.
Human growth factors are proteins naturally occurring in the body, playing crucial roles in cellular communication, repair and rejuvenation processes.
In contrast, BIOEFFECT's growth factors, including the signature Epidermal Growth Factor (EGF), are scientifically developed bio-compatible replicas of human growth factors produced using highly-advanced plant biotechnology.
BIOEFFECT's growth factors are produced using advanced plant biotechnology, with barley plants serving as production hosts. This innovative method ensures the creation of pure, stable, and effective growth factors for our skincare products.
The production process involves:
- Barley plants are used as hosts to produce replicas of human growth factors.
- These engineered barley plants are cultivated in an Icelandic greenhouse powered by sustainable geothermal energy and irrigated with pure Icelandic water, providing optimal growth conditions.
- Once matured, the barley is harvested, and the growth factors are extracted from the barley seed and purified for use in BIOEFFECT's skincare formulations.
This production approach offers advantages such as superior biocompatibility with human growth factors, high purity, and stability.
BIOEFFECT utilizes barley as the host plant for producing growth factors due to its unique advantages. The key reasons include:
- Superior Biocompatibility – Barley-derived growth factors closely replicate human growth factors, ensuring optimal molecular compatibility with the skin.
- Sustainability – Our barley plants are cultivated in a greenhouse in Iceland using sustainable geothermal energy and pure Icelandic water, making the process eco-friendly and minimizing the carbon footprint.
- Stability and Scalability – The growth factors are stored in barley seeds, allowing for long-term stability and consistent, controlled production.
This innovative production process ensures that BIOEFFECT’s skincare products contain highly effective, pure, and ethically sourced growth factors.
Growth factors have become a significant trend in skincare due to their superior efficacy in age-defying skincare, specifically their ability to promote skin regeneration, enhance elasticity, and reduce the appearance of fine lines and wrinkles.
At BIOEFFECT, we incorporate three growth factors in our skincare line, all produced in barley using plant-biotechnology with EGF (Epidermal Growth Factor) being the key signature ingredient.
With expertise in growth factor skincare formulations, BIOEFFECT sets the standard for scientifically advanced skincare—using only a few carefully selected ingredients that the skin truly understands, ensuring that the growth factors remain stable, potent, and effective in the formula.
Yes, BIOEFFECT growth factors are biocompatible with human growth factors. They are designed to mimic the structure and function of naturally occurring human growth factors.
EGF (Epidermal Growth Factor) is a naturally occurring signaling protein that supports essential skin functions, including collagen, elastin, and hyaluronic acid production—key factors in maintaining skin thickness, density, smoothness, and firmness.
BIOEFFECT EGF is a replica of human growth factors, produced using plant biotechnology. It is the age-defying signature ingredient in our skincare line.
Results from scientific studies show that topical application of BIOEFFECT EGF skincare can have a powerful and positive effect on the skin’s appearance—boosting hydration, improving visible skin elasticity and reducing the appearance of wrinkles and fine lines. It has also been shown to help support skin’s natural collagen production to keep skin looking smooth, healthy, and dense.
No. BIOEFFECT's EGF and other growth factors in our skincare are not GMO. The barley plants, the hosts for our growth factor production, are GMO (Genetically Modified Organism)—however, the growth factors themselves are not classified as GMO.
Growth factors and exosomes are both crucial components in regenerative skincare, but they differ significantly in their composition and function. Growth factors are single proteins that promote specific cellular activities such as cell division and collagen production. They are straightforward and effective, targeting particular aspects of skin health. In contrast, exosomes are complex vesicles that carry a diverse array of bioactive molecules, including proteins, lipids, and RNA.
Our growth factors are biocompatible with human growth factors and therefore highly effective in supporting the skin’s natural collagen production, cell repair and regeneration.